Chinese manufacturer directly supply white color Acadesine AICAR cas2629-69-2 from Youngshe

AICAR

product Name: AICAR

Alternate Name/Synonyms: 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; AICA-Riboside;

NSC 105823

Description: A cell- permeable activator of AMP-activated protein kinase (AMPK), a metabolic sensor involved in both cellular and whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle. AICAR is able to activate the molecular circuitry of pluripotency in mESC and to induce the expression of several key regulators of pluripotency in somatic cells.

Peptide Sequence: N/A

Appearance: Tan powder

Formulation: N/A

CAS Number: 2627-69-2

Molecular Formula: C9H14N4O5

Molecular Weight: 258.23

Purity: ≥98% by HPLC

Solubility:H2O

Storage Temp.: -20°C

Shipping Conditions: gel pack

AICAR also known as ZMP is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity (AMPK). AICAR is being clinically used to treat and
protect against cardiac ischemic injury. If left untreated, it may lead to a myocardial infarct.
Cardiac Ischemia is caused by insufficient blood flow and oxygen to the myocardium .
The drug was first used in the 1980’s as a method to preserve blood flow to the heart during surgery. Currently,
the drug has also been shown as a potential treatment for diabetes by increasing the
metabolic activity of tissues by changing the physical composition of muscle.

Application

(1) Applied in phamaceutical field, it is used as phamaceutical raw material to treat injuries from fall,
infectious hepatitis and epidemic cerebrospinal meningitis.
(2) Applied in healthcare field, it is used in the health products to nourish brain,
protect liver and improve sleep quality.
(3) Applied in comestics, it is used to promote skin metabolism and make skin more tender and firm.